This research aims to identify specific cortical surface changes that can differentiate neuromyelitis optica spectrum disorder (NMOSD) from multiple sclerosis (MS).
Longitudinal analysis of cortical surface regions was performed.
Distinct reductions in specific cortical areas were measured over time.
Comparative metrics for NMOSD and MS were assessed.
Longitudinal reductions in cortical regions distinctively separated NMOSD from MS.
Findings support the potential of using cortical metrics to indicate disease activity.
Abstract
Longitudinal reductions in distinct cortical regions may serve as an ideal metric for differentiating NMOSD from MS and may provide evidence of subclinical disease activity.