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April 30, 2026The Journal of Organic Chemistry0 citations

Development of a Protocol for Synthesis of Nitrocinnamonitriles from Nitrotoluenes

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TKTae Won KimJPJinjae ParkCCCheol‐Hong Cheon

Key Points

  • This work aims to develop a protocol for synthesizing nitrocinnamonitriles from nitrotoluenes.
  • Developed a chemical synthesis protocol for nitrocinnamonitriles.
  • Tested compatibility with various substituted aromatic and heteroaromatic systems.
  • Explored the reaction conditions for optimal yields.
  • Demonstrated successful synthesis of nitrocinnamonitriles from nitrotoluenes.
  • Showed compatibility with polysubstituted aromatic rings and broad heteroaromatic systems.

Abstract

to the nitro substituent on the nitrotoluene scaffold. Furthermore, it was compatible with polysubstituted aromatic rings and could be readily extended to a broad range of heteroaromatic systems.

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Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/69f2f0e31e5f7920c6386db3https://doi.org/10.1021/acs.joc.5c03178
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