Copper-Catalyzed Intermolecular Trifluoromethylazidation of Allenamides: An Access to CF3-Containing (E)-Allyl Azides.

Key Points

• This research aims to develop a mild and efficient method for the copper-catalyzed trifluoromethylazidation of allenamides.
• Utilized copper as a catalyst for the trifluoromethylazidation process.
• Tested a broad range of allenamides to assess effectiveness of the method.
• Evaluated the synthesis of various CF3-containing compounds.
• Successfully synthesized a variety of CF3-containing allyl azides.
• Demonstrated efficient method with broad applicability to allenamides.