Normative Gray Matter Stiffness Gradients in the Human Brain Predict Patterns of Cortical Injury after Concussion.

Key Points

• This research aims to explore how gray matter stiffness gradients relate to cortical injury following a concussion.
• Analyzed gray matter microarchitecture using diffusion MRI and magnetic resonance elastography (MRE).
• Evaluated gray matter disruption over the timeline of mild traumatic brain injury (mTBI).
• Identified specific stiffness gradients that correlate with injury patterns after concussion.
• Demonstrated the ability of MRE to detect disruptions in gray matter throughout the mTBI process.