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May 6, 2026Small0 citations

Integration of MOF‐on‐MOF‐Derived Core–Shell CoFe@Fe 3 Mo 3 C with Graphene Oxide@Carbon Nanobubbles for Highly Selective Detection of Flutamide

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YWYilin WangZLZhifang LiuMFMaoheng Fei

Key Points

  • To develop a highly selective electrochemical sensor for Flutamide detection using advanced material integration.
  • Combined MOF-on-MOF-derived materials with graphene oxide and carbon nanobubbles
  • Evaluated the sensor's performance based on conductivity and electrocatalytic activity
  • Conducted density functional theory calculations to understand adsorption energy and reaction mechanisms
  • Achieved a wide linear range of 5.0 nm to 10.0 µm for Flutamide detection
  • Demonstrated an ultralow detection limit of 3.4 nm
  • Recovery rates ranged from 96% to 105% in water sample analyses, indicating effective applicability.

Abstract

C/GO@CNB/GCE electrochemical sensor for Flu detection. Owing to the composite's outstanding conductivity and electrocatalytic activity, the sensor exhibited a wide linear range of 5.0 nm-10.0 µm and an ultralow detection limit of 3.4 nm. Density functional theory calculations showed that the composite possesses the strongest adsorption energy for Flu (-1.50 eV) and elucidated the electrochemical reaction mechanism. The sensor achieved recoveries of 96%-105% in water sample analysis, demonstrating its practical applicability. This study highlights the significant potential of integrating core-shell MOF-on-MOF-derived alloy carbide materials with 2D conductive carbon nanomaterials for environmental analysis.

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69faa1eb04f884e66b532b36https://doi.org/10.1002/smll.202514355
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