What question did this study set out to answer?

The study aims to develop nanocarriers that enhance drug delivery through improved stability and responsiveness.

May 7, 2026Nanoscale0 citations

Thiol-Acrylate Michael Addition Strategy for the Templated Synthesis of Water-Soluble Poly(β-Thioester) Nanogel: Superior Encapsulation Stability and UV-Induced Photolysis Mediated On-Demand Guest Release

AMArun MondalUniversity of Calcutta SSShuvajyoti SarkarUniversity of Calcutta MMMijanur Rahaman MollaUniversity of Calcutta

Key Points

The study aims to develop nanocarriers that enhance drug delivery through improved stability and responsiveness.
Developed a thiol-acrylate Michael addition strategy
Synthesized water-soluble poly(β-thioester) nanogels
Evaluated encapsulation stability and responsiveness to UV-induced photolysis
Nanocarriers exhibited superior encapsulation stability
Demonstrated UV-induced photolysis for controlled guest release
Highlighted tumor-selective responsiveness in drug delivery applications

Abstract

The development of nanocarriers that combine high encapsulation stability, tumor-selective responsiveness, and controlled drug release remains a critical challenge in drug delivery application. Herein, we report a smart nanocarrier platform...

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