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立体反转的 C–O 激活解锁全碳四取代 Z -烯合成 | Synapse

May 7, 2026Journal of the American Chemical Society0 citations

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立体反转的C–O活化开启全碳四取代Z-烯烃合成

KCKaixin Chen JPJiali Peng JLJie Lin

Key Points

探索立体反转C–O活化合成全碳四取代Z-烯烃的潜力。
研究C–O活化技术
合成具有高立体控制的Z-烯烃
评估药物相关分子合成中的产率。
实现了四取代Z-烯烃的高产率合成
在合成过程中显示了有效的立体控制
指出在药物发现和药物化学中具有良好的应用前景。

Abstract

-烯烃。值得注意的是，以高产率和立体控制合成药物分子的简洁过程应突显该技术在药物发现中的应用潜力。

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Cite This Study

Chen等（Mon，）研究了这个问题。

synapsesocial.com/papers/69fbefd5164b5133a91a3ddf https://doi.org/https://doi.org/10.1021/jacs.6c05845

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