Tenecteplase 4.5 to 24 h after non-LVO stroke with potentially salvageable brain tissue improved functional outcomes at 90 d

Key Points

• To assess the effects of tenecteplase on functional outcomes in patients with non-LVO stroke and salvageable brain tissue.
• Randomised clinical trial of tenecteplase administration
• Evaluated patients with non-LVO stroke
• Primary outcome measured at 90 days
• Tenecteplase treatment improved functional outcomes at 90 days
• Effect observed specifically in patients with salvageable brain tissue