Adenosquamous carcinoma (ASC) of the salivary glands is a rare and aggressive malignancy. We report the case of a patient who presented to the otorhinolaryngology department with a two-month history of left parotid swelling associated with peripheral facial nerve paralysis. Imaging revealed an ill-defined, expansive lesion of the left parotid gland with intracranial extension and heterogeneous enhancement following intravenous contrast administration, along with concomitant pulmonary metastases. A surgical biopsy confirmed the diagnosis of primary ASC of the salivary gland. The patient was treated with chemotherapy, with follow-up demonstrating a reduction in the size of the primary tumor and regression of pulmonary metastases. This report highlights the aggressive behavior of this rare entity and underscores the essential role of imaging in its diagnosis and management.
Remok et al. (Mon,) studied this question.