Knowledge, Practices, and Challenges in Deep Venous Thrombosis Prevention Among ICU Nurses: A Cross-Sectional Study

Introduction Intensive care unit patients are at increased risk for deep venous thrombosis, making prevention a key nursing responsibility. Evidence from Saudi Arabia remains limited, particularly regarding intensive care unit nurses’ challenges in implementing deep venous thrombosis prevention measures. Objectives To assess intensive care unit nurses’ knowledge, practices, and challenges related to deep venous thrombosis prevention in selected Saudi tertiary hospitals. Methods A descriptive-correlational, cross-sectional study was conducted among 89 intensive care unit nurses selected through convenience sampling. Data were collected using a self-administered structured questionnaire from March 17 to April 17, 2025. Data analysis employed descriptive and inferential statistical methods, including analysis of variance, Pearson’s correlation coefficient, and frequency and percentage distributions for the challenge items. Results Nurses demonstrated moderate knowledge of deep venous thrombosis prevention (M = 21.14, SD = 8.29), equivalent to 62.2% of the total possible knowledge score. Practice was generally favorable (M = 14.70, SD = 4.59), with 58.4% classified as having good practice. Knowledge and practice were positively associated (r = 0.486, p < .001). Commonly reported challenges included knowledge gaps, barriers to patient mobilization, resource constraints, and communication issues within the healthcare team. Conclusion Intensive care unit nurses demonstrated moderate knowledge and generally favorable practice regarding deep venous thrombosis prevention. Higher knowledge was associated with better practice. Targeted education and organizational support may help strengthen prevention in critical care settings.