Evaluation of Genetics in the Association Between Cardiorespiratory Fitness and Health

Key Points

• This research investigates how genetics relate to cardiorespiratory fitness (CRF) and its effects on health outcomes.
• Evaluated genome-wide polygenic scores (PGS) for their association with CRF phenotype.
• Analyzed links between genetic variations and incidences of Type 2 Diabetes (T2D).
• Genome-wide PGS accounts for a small portion of CRF phenotype variation.
• Some links between genetic factors and T2D incidence were detected.