Fluid Restriction Enhances Mitochondrial Stress in Peripheral Blood Mononuclear Cells Following High-Volume Resistance Exercise in Health Young Males

Key Points

• This research investigates the effect of fluid restriction on mitochondrial stress in peripheral blood mononuclear cells after resistance exercise.
• Examined the impact of 24 hours of fluid restriction before high-volume resistance exercise on PBMCs and serum levels of IL-6 and CRP.
• Measured changes in mitochondrial quality control and inflammatory markers in healthy young males.
• PBMCs exhibited elevated mitochondrial stress markers after fluid restriction compared to hydration.
• Serum IL-6 and CRP levels were significantly higher in the fluid restriction group than the hydration group.