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May 9, 20260 citationsOpen Access

Epitope mapping of Treponema Pallidum by SPOT synthesis combined with microscale thermophoresis to guide the development of chimeric antigens for syphilis immunodiagnostics

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JWJessica WatermanPPPaloma PegoBSBarbara Succar

Key Points

  • The research aims to map epitopes of Treponema pallidum to inform the design of chimeric antigens for syphilis diagnosis.
  • Used SPOT synthesis for epitope mapping.
  • Employed microscale thermophoresis to analyze binding interactions.
  • Focused on developing chimeric antigens for immunodiagnostics.
  • Identified key epitopes for Treponema pallidum.
  • Developed potential chimeric antigens that could enhance syphilis detection.

Abstract

Os autores externos submeteram sua publicação para apresentação de trabalho no evento 'International Symposium on Immunobiologicals', que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.

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Cite This Study

Waterman et al. (2026) studied this question.

synapsesocial.com/papers/69fecf16b9154b0b828762e1https://doi.org/10.35259/isi.2026_76237
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