A G57 (BJ/94-like) H9N2 avian influenza virus exhibits enhanced replication and tissue dissemination in chickens compared with a G1-B virus

Key Points

• The aim is to investigate how the G57 (BJ/94-like) H9N2 avian influenza virus replicates and spreads in chickens compared to a G1-B virus.
• Comparison of replication rates and tissue dissemination between G57 and G1-B H9N2 viruses in chickens.
• Analysis of viral fitness through reassortment involving G57 genotype genes.
• The G57 avian influenza virus demonstrated enhanced replication in chickens compared to the G1-B virus.
• Increased tissue dissemination was noted with the G57 virus, suggesting greater viral spread.