Sodium channel blockade in individuals with loss-of-function SCN5A mutations yields complex phenotypes, leaving its safety and clinical utility in Brugada syndrome uncertain.
Is sodium channel blockade in individuals with loss-of-function sodium channel mutations dangerous or helpful?
This editorial discusses the clinical profile and prognosis of Brugada syndrome SCN5A variant carriers with a negative sodium channel blocker challenge.
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This editorial refers to ‘Clinical profile and prognosis of brugada syndrome SCN5A variant carriers with negative sodium channel blocker challenge’ by E. Surget et al. , https:
P G Postema (Wed,) reported a other. Sodium channel blockade in individuals with loss-of-function SCN5A mutations yields complex phenotypes, leaving its safety and clinical utility in Brugada syndrome uncertain.