What question did this study set out to answer?

This study aims to assess the short-term optical performance and efficacy of the ZEISS CT LUCIA 621P intraocular lens in cataract patients based on IOL power variations.

May 13, 2026Clinical ophthalmology0 citationsOpen Access

Short-Term Visual and Optical Performance of the ZEISS CT LUCIA 621P Intraocular Lens Across Different Power Ranges

JJJiwon JeongKim's Eye Hospital YKYounghee KimKim's Eye Hospital DKDong Wook KimGyeongsang National University

Key Points

This study aims to assess the short-term optical performance and efficacy of the ZEISS CT LUCIA 621P intraocular lens in cataract patients based on IOL power variations.
Retrospective analysis of 304 eyes from 216 patients undergoing phacoemulsification with CT LUCIA 621P implantation.
Patients stratified into four groups based on implanted IOL power: <20.0 D, 20.0–21.5 D, 22.0–23.5 D, and ≥24.0 D.
Primary outcomes included photopic/mesopic defocus curves and higher-order aberrations at 1 and 3 months post-surgery.
All groups achieved excellent refractive predictability (p=0.398).
Mean monocular uncorrected distance visual acuity at 3 months showed no significant difference among groups (p=0.498).
Photopic contrast sensitivity remained comparable across IOL power groups at most spatial frequencies.

Abstract

Purpose: To evaluate the short-term efficacy and optical performance of the ZEISS CT LUCIA 621P intraocular lens (IOL) in cataract patients using a diopter (D)-stratified approach. Patients and Methods: This retrospective study included 304 eyes of 216 patients who underwent phacoemulsification with CT LUCIA 621P implantation. Eyes were stratified into four groups by implanted IOL power: Group 1 ( 0.23). Photopic and mesopic defocus curves showed similar depth of focus across groups (p> 0.05 at most levels). Postoperative spherical aberration (SA) and coma remained low with no significant inter-group differences after generalized GEE adjustment (p> 0.17). Photopic CS was comparable across IOL power groups at most spatial frequencies. Conclusion: The CT LUCIA 621P IOL demonstrated consistent refractive predictability, VA across distances, and optical quality across a wide range of implanted powers, supporting its reliable use in contemporary cataract surgery. Keywords: CT LUCIA 621P, non-constant aspheric IOL, ZEISS optic, diopter-stratified analysis, visual performance, optical quality, cataract surgery

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Cite This Study

Jeong et al. (Fri,) studied this question.

synapsesocial.com/papers/6a04141c79e20c90b44444ce https://doi.org/https://doi.org/10.2147/opth.s611427

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