Enzyme-free Regioselective Phosphorylation of Ribonucleosides is Promoted by Metal Ions

Key Points

• The study investigates how metal ions promote regioselective phosphorylation of ribonucleosides under prebiotic conditions.
• Analyzed the impact of various metal ions on the phosphorylation process
• Used ribonucleosides as model molecules in experiments
• Metal ions significantly enhanced phosphorylation rates of ribonucleosides
• The regioselectivity of phosphorylation was influenced by specific metal ions allowing targeted outcomes