Left Ventricular Mass as a Confounder of Stress CMR and Invasive Coronary Angiography Concordance: Mechanistic Insights and Clinical Implications

Key Points

• This research aims to explore the role of left ventricular mass as a confounder in the agreement between stress CMR and invasive coronary angiography.
• Analyzed data from cardiac imaging, specifically stress CMR and coronary angiography.
• Considered left ventricular mass measurements as potential confounding factors in diagnostic evaluations.
• Examined mechanistic insights using statistical models to understand clinical implications.
• Found a significant correlation between left ventricular mass and discrepancies in diagnostic outcomes.
• Demonstrated that increased left ventricular mass led to lower concordance rates between stress CMR and angiography results.
• Highlighted the need for careful interpretation of stress CMR in patients with elevated left ventricular mass.