Scaffolds toughen bacteria-based therapy

Key Points

• The aim is to explore how stiff hydrogel scaffolds can enhance the delivery of therapeutic molecules via bacteria.
• Developed tough hydrogel layers to host bacteria.
• Evaluated the release dynamics of therapeutic molecules from these scaffolds.
• Sustained release of therapeutic molecules was observed from the hydrogel scaffolds.
• The hydrogel's stiffness contributed significantly to the improved delivery efficiency.