Diastolic dysfunction is associated with a high risk for arrhythmic death or resuscitated cardiac arrest regardless of whether LVEF is ≤35% or >35% (P<0.001).
Cohort (n=210)
Does diastolic dysfunction predict arrhythmic death or resuscitated cardiac arrest in patients with cardiomyopathy or normal LVEF?
Diastolic dysfunction grading may improve risk stratification for arrhythmic death and resuscitated cardiac arrest, independent of LVEF.
p-value: p=<0.001
BACKGROUND: Patients with ischemic or dilated cardiomyopathy and reduced left ventricular ejection fraction (LVEF) face a high risk for ventricular arrhythmias. Exact grading of diastolic function might improve risk stratification for arrhythmic death. METHODS: We prospectively enrolled 120 patients with ischemic, 60 patients with dilated cardiomyopathy, and 30 patients with normal LVEF. Diastolic function was graded normal (N) or dysfunction grade I to III. Primary outcome parameter was arrhythmic death (AD) or resuscitated cardiac arrest (RCA). RESULTS: 35%. Diastolic function grading might improve risk stratification for AD.
Pezawas et al. (2020) conducted a cohort in Ischemic or dilated cardiomyopathy (n=210). Diastolic dysfunction vs. Normal diastolic function was evaluated on Arrhythmic death (AD) or resuscitated cardiac arrest (RCA) (p=<0.001). Diastolic dysfunction is associated with a high risk for arrhythmic death or resuscitated cardiac arrest regardless of whether LVEF is ≤35% or >35% (P<0.001).
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