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August 5, 2020New England Journal of Medicine163 citations

Native-Valve Infective Endocarditis

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HCHenry F. ChambersABArnold S. Bayer

Key Result

Diagnosis of native-valve infective endocarditis is based on modified Duke criteria, with management depending on culture-guided antibiotic therapy and early surgery in select cases.

Structured PICO

P
Population
Patients with native-valve infective endocarditis
I
Intervention
Diagnosis (modified Duke criteria) and management (culture-directed antibiotics, early surgery)

This review outlines the diagnosis of native-valve infective endocarditis using modified Duke criteria and its management with culture-directed antibiotics and early surgery.

Abstract

The diagnosis of infectious endocarditis is based on modified Duke criteria, according to findings on physical examination, echocardiography, microbiologic studies, and imaging of target organs. The selection and duration of antibiotic treatment depend on culture results. Early surgery is indicated in some patients.

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Cite This Study

Chambers et al. (2020) studied this question. Diagnosis of native-valve infective endocarditis is based on modified Duke criteria, with management depending on culture-guided antibiotic therapy and early surgery in select cases.

synapsesocial.com/papers/6a08e100451dd5ba805b66d3https://doi.org/10.1056/nejmcp2000400
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