The Quantitative Insulin Sensitivity Check Index (QUICKI) is a validated surrogate marker for estimating insulin resistance in individuals at elevated metabolic risk. QUICKI demonstrates strong correlation with gold standard measurements, particularly in patients with obesity, type 2 diabetes, and metabolic syndrome, but performs sub-optimally in healthy or African American cohorts. While not recommended for individual diagnosis, QUICKI remains a valuable non-invasive tool for population-level research. This review outlines its clinical utility, strengths, and limitations.
Jayachidambaram Ambalavanan (Thu,) studied this question.