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Background: Tc-pyrophosphate (PYP) uptake, but real-world performance is uncertain. Methods and Results: We reviewed 102 consecutive patients who underwent PYP scintigraphy; grade ≥2 was positive, and grade 1 equivocal/negative. Of them, 15 were positive; 11 had scores 0-1 yet were positive, while 8 scored 2 and yet were negative. Adding age, sex, PR interval, and atrial fibrillation improved the area under the curve (AUC) from 0.598 to 0.866; excluding sex yielded AUC 0.842. Conclusions: Using the Kumamoto criteria alone showed limited discrimination; combining routine variables may help select patients for PYP scintigraphy.
Aoyama et al. (Fri,) studied this question.