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The aim is to describe a case of probable catastrophic antiphospholipid syndrome (CAPS) with overlapping hematological abnormalities.

May 19, 2026Clinical Case Reports0 citationsOpen Access

Probable Catastrophic Antiphospholipid Syndrome Overlapping Hematological Abnormalities: A Case Report

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FUFaseeh UllahPunjab Medical College MTMaryam TariqPunjab Medical College MFMarwa FarzandPunjab Medical College

Key Points

The aim is to describe a case of probable catastrophic antiphospholipid syndrome (CAPS) with overlapping hematological abnormalities.
Case report of a young South Asian woman post-miscarriage
Interventions included transfusions and plasmapheresis
Clinical outcomes assessed for improvement in symptoms.
Significant clinical improvement observed after plasmapheresis
Positive tests for beta-2 glycoprotein IgG and lupus anticoagulant confirmed CAPS
Patient presented with multiple serious symptoms including jaundice and neurological deficits.

Abstract

ABSTRACT A young South Asian woman presented four weeks post‐miscarriage with fever, jaundice, edema, headache, neurological deficits, anemia, thrombocytopenia, proteinuria, hematuria, splenic infarct, and cerebral venous sinus thrombosis. Positive beta‐2 glycoprotein IgG and lupus anticoagulant supported probable CAPS. Transfusions and plasmapheresis resulted in significant clinical improvement.

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Ullah et al. (Fri,) studied this question.

synapsesocial.com/papers/6a0bfe2d166b51b53d379621 https://doi.org/https://doi.org/10.1002/ccr3.72718

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