GO/APTES-mediated bifunctional CuFe 2 O 4 @GO-NH 2 -facilitated synthesis of pyrazolo-triazepine scaffolds as a potent post-prandial antidiabetic agent against dual α-amylase and α-glucosidase enzymes

Key Points

• The aim is to explore the synthesis of pyrazolo-fused triazepine scaffolds for their antidiabetic activity.
• Utilized CuFe2O4@GO-NH2 for synthesis
• Conducted multidimensional analysis for efficacy against α-amylase and α-glucosidase enzymes
• Demonstrated significant inhibition of α-amylase with specific activity compared to controls
• Showed potent inhibition of α-glucosidase, indicating effectiveness as an antidiabetic agent