Effect of Hydroxyurea on Transfusion Requirements in Pediatric β-Thalassemia: A Quasi-Experimental Study

Key Points

• The study aims to assess how hydroxyurea influences transfusion requirements in children with β-thalassemia.
• Quasi-experimental design
• Evaluated transfusion burden in Pakistani children
• Monitored changes in transfusion needs pre- and post-intervention
• Reduction in transfusion frequency observed after hydroxyurea treatment
• Improvement in hemoglobin levels recorded with hydroxyurea administration