Fluorous Nanoemulsion Optodes with Förster Resonance Energy Transfer-Based Fluorescence Amplification Toward Highly-Sensitive and Selective Detection of Perfluorooctanesulfonate

Key Points

• This study aims to develop a highly sensitive method for detecting perfluorooctanesulfonate (PFOS) using fluorous nanoemulsion optodes.
• Investigated fluorescence enhancement through Förster resonance energy transfer (FRET)
• Incorporated fluoroalkyl-containing donor and acceptor materials
• Evaluated sensitivity and selectivity in the detection of PFOS
• Significant fluorescence enhancement was observed for PFOS detection with optimal sensitivity.
• Achieved detection limits lower than existing methods, indicating superior performance.
• Demonstrated selective binding of PFOS with minimal interference from other compounds.