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Investigators are beginning to exploit the pericardial space for a number of cardiovascular applications, including catheter ablation of cardiac arrhythmias, cardiovascular drug therapy, and cardiac pacing. This review explores the anatomy of the pericardial space and the anatomic variants that may be encountered in this novel approach to the heart.
d’Ávila et al. (2003) studied this question. The pericardial space and its anatomic variants are increasingly utilized for novel cardiovascular applications, including catheter ablation of arrhythmias, drug therapy, and cardiac pacing.