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May 25, 2026Molecular and Cellular Biology0 citationsOpen Access

The Yeast AP-1 Factor Yap8 Recruits SAGA and SWI/SNF to Regulate ACR3 Expression and Arsenic Tolerance

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EMEwa Maciaszczyk-DziubińskaARAntonia M. RomeroNKNallani Vijay Kumar

Key Points

  • This research investigates the role of the Yap8 protein in regulating arsenic tolerance through ACR3 expression.
  • Utilized molecular techniques to analyze Yap8 function in yeast.
  • Examined recruitment of SAGA and SWI/SNF complexes to target genes.
  • Assessed the impact of Yap8 on arsenic tolerance.
  • Yap8 significantly enhances ACR3 expression, leading to increased arsenic tolerance.
  • Recruitment of SAGA and SWI/SNF by Yap8 is crucial for this regulation.

Abstract

The AP-1-like protein Yap8 is required for arsenic tolerance in the yeast

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Cite This Study

Maciaszczyk-Dziubińska et al. (2026) studied this question.

synapsesocial.com/papers/6a13e7e80e02ee3982d32894https://doi.org/10.1080/10985549.2026.2671974
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1[10] Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast1983 · 1,096 citations
  2. 2Yap, a Novel Family of Eight bZIP Proteins in Saccharomyces cerevisiae with Distinct Biological Functions1997 · 317 citations
  3. 3Isolation of Three Contiguous Genes,ACR1,ACR2 andACR3, Involved in Resistance to Arsenic Compounds in the YeastSaccharomyces cerevisiae1997 · 231 citations
  4. 4Histone Acetyltransferase Complexes Stabilize SWI/SNF Binding to Promoter Nucleosomes2001 · 367 citations
  5. 5Transcriptional Profiling Shows that Gcn4p Is a Master Regulator of Gene Expression during Amino Acid Starvation in Yeast2001 · 768 citations