Allergic Conjunctivitis (AC) is a common immune-related ocular surface disease in children, characterized by a prolonged course and frequent recurrence, which severely impacts patients' quality of life. With its rising global incidence, modern medicine primarily relies on topical anti-allergic treatments that, while controlling symptoms, have limitations in long-term efficacy and recurrence prevention. In contrast, Traditional Chinese Medicine (TCM) offers unique advantages in symptomatic improvement and prevention through holistic management. Based on the emerging "gut-eye axis" theory, this article explores the pathological mechanisms of gut microbiota involvement in AC and the close relationship between the Spleen in TCM and gut microbiota. It proposes that the pathogenesis of pediatric AC stems from "Spleen deficiency as the root, Dampness accumulation as the basis, and Wind-Phlegm attacking the eyes." Emphasizing strengthening the Spleen as the fundamental treatment principle, this paper discusses AC prevention and management from three aspects—"prevention before disease onset, prevention of exacerbation during disease, and prevention of recurrence after disease"—aiming to expand TCM diagnostic and therapeutic approaches for pediatric AC.
Zeng et al. (Thu,) studied this question.