Cisplatin-based chemotherapy was associated with late severe vascular toxicity, including hypertension, acute myocardial infarction, and cerebrovascular accident, in a 19-year-old man.
Case Report (n=1)
Highlights severe late vascular toxicities, including myocardial infarction and stroke, associated with cisplatin-based chemotherapy.
A 19-year-old man with a germ cell tumor who experienced hypertension, acute myocardial infarction, and cerebrovascular accident (CVA) associated with hypomagnesemia as late complications of cisplatin-based chemotherapy is presented, and previously reported cases in the literature are reviewed. Different physiopathologic mechanisms are hypothesized for early and late vascular complications of cisplatin.
İçlı et al. (1993) conducted a case report in Germ cell tumor (n=1). Cisplatin-based chemotherapy was evaluated on Severe vascular toxicity (hypertension, acute myocardial infarction, and cerebrovascular accident). Cisplatin-based chemotherapy was associated with late severe vascular toxicity, including hypertension, acute myocardial infarction, and cerebrovascular accident, in a 19-year-old man.