Key result
Cisplatin-based chemotherapy was associated with late severe vascular toxicity, including hypertension, acute myocardial infarction, and cerebrovascular accident, in a 19-year-old man.
Case Report (n=1)
Highlights severe late vascular toxicities, including myocardial infarction and stroke, associated with cisplatin-based chemotherapy.
Suggests vigilance for late vascular events in young cisplatin recipients; hypothesis-generating case extending prior reports, needs prospective confirmation.
A 19-year-old man with a germ cell tumor who experienced hypertension, acute myocardial infarction, and cerebrovascular accident (CVA) associated with hypomagnesemia as late complications of cisplatin-based chemotherapy is presented, and previously reported cases in the literature are reviewed. Different physiopathologic mechanisms are hypothesized for early and late vascular complications of cisplatin.
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İçlı et al. (1993) conducted a case report in Germ cell tumor (n=1). Cisplatin-based chemotherapy was evaluated on Severe vascular toxicity (hypertension, acute myocardial infarction, and cerebrovascular accident). Cisplatin-based chemotherapy was associated with late severe vascular toxicity, including hypertension, acute myocardial infarction, and cerebrovascular accident, in a 19-year-old man.
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