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July 7, 2021International Journal of Cardiovascular Sciences9 citationsOpen Access

Validation of the Grace Risk Score to Predict In-Hospital and 6-Month Post-Discharge Mortality in Patients with Acute Coronary Syndrome

VNVítor Boniatti NevesRRRaquel Melchior RomanTVTiago P. Vendruscolo

Key Result

The GRACE risk score accurately predicted in-hospital mortality (AUC 0.76) and 6-month post-discharge mortality (AUC 0.78) in patients with acute coronary syndrome.

Study Design

Type

Cohort (n=160)

Multicenter

No

Structured PICO

Does the GRACE risk score predict in-hospital and 6-month post-discharge mortality in patients with acute coronary syndrome?

P
Population
Consecutive patients diagnosed with acute coronary syndrome (ACS)
I
Intervention
Global Registry of Acute Coronary Events (GRACE) risk score
O
Outcome
In-hospital and 6-month post-discharge mortalityhard clinical

This study evaluates the validity of the GRACE risk score for predicting in-hospital and 6-month mortality in patients with acute coronary syndrome.

Main Result

Effect estimate: AUC 0.76 (95% CI 0.57-0.95)

p-value: p=0.014

Limitations

  • No exploratory analysis of factors related to mortality
  • No analysis of the impact of prescribed pharmacological and interventional treatments

Abstract

Background The wide range of clinical presentations of acute coronary syndrome (ACS) makes it indispensible to use tools for risk stratification and for appropriate risks management; thus, the use of prognosis scores is recommended in the immediat clinical decision-making. Objective To validate the Global Registry of Acute Coronary Events (GRACE) score as a predictor of in-hospital and 6-month post-discharge mortality in a population diagnosed with ACS. Methods This is a prospective cohort study of consecutive patients diagnosed with ACS ...

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Cite This Study

Neves et al. (2021) conducted a cohort in Acute Coronary Syndrome (n=160). GRACE Risk Score was evaluated on In-hospital mortality prediction (AUC 0.76, 95% CI 0.57-0.95, p=0.014). The GRACE risk score accurately predicted in-hospital mortality (AUC 0.76) and 6-month post-discharge mortality (AUC 0.78) in patients with acute coronary syndrome.

synapsesocial.com/papers/6a1785fc7afe20c06351e047https://doi.org/10.36660/ijcs.20210019
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