Does 1-year moderate-to-vigorous aerobic exercise training alter cerebral vasomotor reactivity and improve cognitive performance in older adults with amnestic mild cognitive impairment?
One year of moderate-to-vigorous aerobic exercise training alters cerebral vasomotor reactivity in patients with mild cognitive impairment, and these physiological changes correlate with improved memory and executive function.
One-year moderate-to-vigorous intensity aerobic exercise training (AET) improved cardiorespiratory fitness (V̇o 2peak ), increased hypocapnic cerebral vasomotor reactivity (CVMR), whereas it decreased hypercapnic CVMR when compared with stretching and toning in patients with amnestic mild cognitive impairment (MCI). Furthermore, changes in hypercapnic CVMR with AET were correlated with improved memory and executive function. These findings indicate that AET has an impact on cerebrovascular function which may benefit cognitive performance in older adults who have high risk of Alzheimer’s disease.
Tomoto et al. (Thu,) studied this question.