When and How to Deviate From a Preregistration

As the practice of preregistration becomes more common, researchers need guidance in how to report deviations from their preregistered statistical analysis plan. A principled approach to the use of preregistration should not treat all deviations as problematic. Deviations from a preregistered analysis plan can both reduce and increase the severity of a test, as well as increase the validity of inferences. I provide examples of how researchers can present deviations from preregistrations and evaluate the consequences of the deviation when encountering 1) unforeseen events, 2) errors in the preregistration, 3) missing information, 4) violations of untested assumptions, and 5) falsification of auxiliary hypotheses. The current manuscript aims to provide a principled approach to deciding when to deviate from a preregistration and how to report deviations from an error-statistical philosophy grounded in methodological falsificationism. The goal is to help researchers reflect on the consequence of deviations from preregistrations by evaluating the test’s severity and the validity of the inference.