Gynecological disorders such as Polyendocrine Metabolic Ovarian Syndrome (PMOS), obesity-related infertility, uterine fibroids, dysmenorrhea, menorrhagia, and leucorrhoea are increasingly prevalent due to sedentary lifestyle, improper dietary habits, stress, and metabolic disturbances. In Ayurveda, many of these conditions are primarily associated with Kapha-Meda dushti, Agnimandya, Ama formation, and obstruction of Artavavaha srotas. Charaka Samhita describes Lekhaniya Mahakashaya as a group of ten herbs possessing Lekhana (scraping), Medohara, Deepana, Pachana, and Srotoshodhana properties, which help eliminate pathological accumulations and restore normal physiological functions. The present review highlights the role of Lekhaniya Mahakashaya in gynecological diseases from both Ayurvedic and modern perspectives. The drugs included in this Mahakashaya exhibit significant anti-inflammatory, antioxidant, hypolipidemic, antimicrobial, and endocrine-regulating activities. These properties help in reducing obesity, correcting hormonal imbalance, improving insulin sensitivity, regulating menstrual cycles, reducing abnormal tissue growth, and enhancing reproductive health. By clearing channel obstruction and improving tissue metabolism, Lekhaniya Mahakashaya supports proper functioning of the female reproductive system. The combined pharmacological and Ayurvedic actions of these herbs make them particularly useful in the management of Kapha-dominant gynecological disorders. The review suggests that Lekhaniya Mahakashaya offers a holistic and cost-effective therapeutic approach for gynecological diseases, especially those associated with metabolic syndrome and hormonal dysfunction. Further clinical and experimental studies are recommended to validate its efficacy and establish evidence-based therapeutic applications in modern gynecological practice.
*1Dr. Anuradha Gupta, 2Dr. Anjana Saxena, 3Dr. Shashi Singh (Mon,) studied this question.