Why the study?
Syncope can result from serious cardiac conditions or other causes, prompting a review of the accuracy of the clinical examination for identifying cardiac syncope.
Does the clinical examination accurately identify cardiac syncope in adults presenting with syncope?
Comparison
Clinical examination vs independent reference standard
Design
Systematic review
Key result
Clinical examination features, including age ≥35 years (LR 3.3; 95% CI 2.6-4.1) and history of atrial fibrillation (LR 7.3; 95% CI 2.4-22), accurately identify patients with cardiac syncope.
Authors
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Age ≥35 years and AF history aid cardiac syncope identification at presentation; confirms accuracy of targeted clinical examination in syncope evaluation.
Systematic Review (n=4,317)
Does the clinical examination accurately identify cardiac syncope in adults presenting with syncope?
Specific clinical examination findings and multivariable scores like EGSYS can accurately help identify or rule out cardiac causes of syncope.
Albassam et al. (2019) conducted a systematic review in Cardiac syncope (n=4,317). Clinical examination vs. Reference standard was evaluated on Sensitivity, specificity, and likelihood ratios (LRs) for identifying cardiac syncope. Clinical examination features, including age ≥35 years (LR 3.3; 95% CI 2.6-4.1) and history of atrial fibrillation (LR 7.3; 95% CI 2.4-22), accurately identify patients with cardiac syncope.
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