Why the study?
The study was designed to evaluate the clinical profile of patients with syncope and assess the usefulness of various clinical tests to determine the diagnosis and etiology of syncope.
What is the diagnostic yield of various clinical investigations in patients presenting with syncope?
Population
90 consecutive patients aged ≥ 12 years presenting with syncope
Design
Cross-sectional, observational study
Key result
Head-up tilt table testing (HUTT) had the highest diagnostic yield, identifying the etiology of syncope in 74% of cases, whereas ECG determined the etiology in 8% of cases.
Authors
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Supports targeted HUTT after initial ECG in syncope; hypothesis-generating, leaves open prospective validation before practice change.
Cross-Sectional (n=90)
No
What is the diagnostic yield of various clinical investigations in patients presenting with syncope?
Initial evaluation of syncope should focus on history, physical examination, and ECG to guide further high-yield testing and reduce diagnostic costs.
Uppoor et al. (2022) conducted a cross-sectional in Syncope (n=90). Diagnostic investigations (ECG, Holter, HUTT, etc.) was evaluated on Diagnostic yield of various clinical investigations. Head-up tilt table testing (HUTT) had the highest diagnostic yield, identifying the etiology of syncope in 74% of cases, whereas ECG determined the etiology in 8% of cases.
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