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August 1, 2006The Journal of Nervous and Mental Disease

Functional disability and social adjustment in major depressive disorder were predicted by depression severity, recurrence, lack of full remission, time spent depressed, and comorbidities.

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Why the study?

What factors influence social and occupational disability and social adjustment among patients with major depressive disorder?

Population

193 psychiatric inpatients and outpatients with major depressive disorder in Vantaa, Finland

Design

Cohort

Follow-up

6 and 18 months

Key result

Functional disability and social adjustment in major depressive disorder were predicted by depression severity, recurrence, lack of full remission, time spent depressed, and comorbidities.

Authors

HRHeikki RytsäläTMTarja MelartinULUlla S. Leskelä

Discussion

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Overview

May guide monitoring of MDD severity and remission to limit disability; leaves open whether targeted interventions improve outcomes.

Study Design

Type

Cohort (n=269)

Multicenter

No

Structured PICO

What factors influence social and occupational disability and social adjustment among patients with major depressive disorder?

P
Population
193 psychiatric inpatients and outpatients with major depressive disorder in Vantaa, Finland
O
Outcome
Global disability and social and work adjustmentpatient reported

Functional disability and social adjustment in major depressive disorder are strongly predicted by depression severity, recurrence, and psychiatric comorbidities.

Cite This Study

Rytsälä et al. (2006) conducted a cohort in Major depressive disorder (n=269). Functional disability and social adjustment in major depressive disorder were predicted by depression severity, recurrence, lack of full remission, time spent depressed, and comorbidities.

synapsesocial.com/papers/6a1c54f51567d2fc4d5ff206https://doi.org/10.1097/01.nmd.0000230394.21345.c4
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