PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
June 1, 20260 citations

Evaluating the Efficacy of Dexmedetomidine as an Adjunct to Local Anesthetics in Adductor Canal Blocks for Adult Patients Undergoing Primary Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.

View Full Paper
WBWilliam BeldenMCMaria Ciceron-VelazquezYLYo Lee

Key Points

  • The study aims to assess the effectiveness of dexmedetomidine as an adjunct to local anesthetics in enhancing analgesia during knee surgeries.
  • Conducted a systematic review and meta-analysis of studies evaluating dexmedetomidine in adductor canal blocks.
  • Included analyses of time to first rescue analgesia and ambulation outcomes.
  • Considered heterogeneity among included studies.
  • Dexmedetomidine increased time to first rescue analgesia by 1.54 hours.
  • Ambulation outcomes improved for patients receiving dexmedetomidine.
  • Significant heterogeneity was noted, limiting generalizability of results.

Abstract

= .05). Time to first rescue analgesia increased by 1.54 hours, and ambulation outcomes consistently showed improvement in the dexmedetomidine group. This analysis supports the use of dexmedetomidine as an adjunct for ACB in TKA. However, significant heterogeneity among studies limits applicability of this analysis's findings. Clinicians are advised to consider this when making practice decisions.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Belden et al. (2026) studied this question.

synapsesocial.com/papers/6a1d23a102fbce9130639150https://doi.org/10.70278/aanaj/.0000001071
Ask AI
Helpful
Bookmark
Share
View Full Paper