Systematic review evaluates dexmedetomidine’s impact on analgesia in total knee arthroplasty, suggesting improved outcomes.
= .05). Time to first rescue analgesia increased by 1.54 hours, and ambulation outcomes consistently showed improvement in the dexmedetomidine group. This analysis supports the use of dexmedetomidine as an adjunct for ACB in TKA. However, significant heterogeneity among studies limits applicability of this analysis's findings. Clinicians are advised to consider this when making practice decisions.
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Belden et al. (2026) studied this question.
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