Why the study?
Alpha-2 agonists such as dexmedetomidine have been considered as adjuvants to improve anesthesia quality, and this study aimed to evaluate dexmedetomidine as an adjunct to bupivacaine in spinal anesthesia for orthopedic surgery.
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Population
Patients undergoing femoral fracture orthopedic surgery
Comparison
Dexmedetomidine as an adjunct to bupivacaine vs bupivacaine alone
Design
Double-blind randomized clinical trial
Dexmedetomidine adjunct may prolong analgesia and reduce opioid needs after femoral fracture surgery; extends spinal anesthesia evidence in orthopedic trauma.
Introduction: Various drugs are used as adjuvants for various purposes such as increasing analgesia, reducing analgesic complications and generally improving the quality of anesthesia with topical anesthetics. The use of alpha-2 agonists has recently been considered. One of these drugs is dexmedetomidine, which has been studied recently. The aim of this study was to evaluate the effect of dexmedetomidine as an adjunct to bupivacaine in spinal anesthesia in femoral fracture orthopedic surgery.
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Rastegarian et al. (2020) studied this question.
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