Higher cardiovascular health scores were inversely associated with nocturnal diastolic blood pressure variability (B-coefficient -0.175; 95% CI -0.271 to -0.078; P<0.001 per 10-point increase).
Cross-Sectional (n=4,447)
Is a higher cardiovascular health score associated with lower short-term blood pressure variability in Chinese adults?
Higher cardiovascular health scores based on the AHA's 'Life's Essential 8' are associated with lower short-term diastolic blood pressure variability in Chinese adults.
Effect estimate: B-coefficient -0.175 (95% CI -0.271 to -0.078)
p-value: p=<0.001
Objective: Increased blood pressure variability (BPV) exerts independent predictive value on several health outcomes including cardiovascular events. To better quantify cardiovascular health (CVH), the American Heart Association (AHA) recently introduced new algorithms called “Life's Essential 8” score. The present study aims to investigate the association between the newly defined CVH assessment and BPV in Chinese adults. Design and method: A total of 4447 individuals who underwent 24-h ambulatory blood pressure (BP) monitoring and complete “Life's Essential 8” data were enrolled in this cross-sectional study. BPV was measured by coefficient of variation (CV), variability independent of the mean (VIM), and standard deviation (SD) of blood pressure measurements. We calculated the overall CVH score (range 0 lowest to 100 highest), as well as the score for each component of diet, physical activity (PA), nicotine exposure, sleep duration, body mass index (BMI), blood lipids, blood glucose, and BP, based on the published AHA definitions. Multivariate linear regression models were performed to establish the association between CVH-score and BPV. Results: The mean age was 60.6±10.9 years, with 3236 males (72.77%). Multivariable linear regression analysis revealed that higher CVH score was inversely associated with diurnal and nocturnal diastolic BPV(DBPV), which persisted after adjusting for mean BP levels and other risk factors. Per 10-point increase in CVH-score, the B-coefficient (95% confidence interval) for diurnal DBPV-SD, DBPV-CV and DBPV-VIM was -0.115(-0.196, -0.033), -0.129(-0.229, -0.028), and -0.006(-0.100, -0.001), all P <0.05, and for nocturnal DBPV-SD, DBPV-CV and DBPV-VIM was -0.175(-0.271, -0.0780), -0.220(-0.346, -0.095), and -0.0104(-0.0161, -0.00461), all P<0.001. Further sensitivity analyses indicated the consistent relationship between nocturnal DBPV and CVH score in subjects with hypertension or not and without antihypertensive drugs. Conclusions: The study adopted that a healthy lifestyle was related to a lower DBPV in Chinese adults, which supporting that ideal CVH metrics may contribute to better blood pressure management.
Sijin Zhang (Fri,) conducted a cross-sectional in Blood pressure variability (n=4,447). Cardiovascular health score (Life's Essential 8) vs. Lower cardiovascular health score was evaluated on Nocturnal diastolic blood pressure variability (DBPV-SD) (B-coefficient -0.175, 95% CI -0.271 to -0.078, p=<0.001). Higher cardiovascular health scores were inversely associated with nocturnal diastolic blood pressure variability (B-coefficient -0.175; 95% CI -0.271 to -0.078; P<0.001 per 10-point increase).