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September 1, 1995Pacing and Clinical Electrophysiology72 citations

Effects of Electroporation on Transmembrane Potential Induced by Defibrillation Shocks

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Population

One-dimensional model of cardiac strand

Design

Preclinical

Authors

WKWanda Krassowska

Discussion

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Overview

Electroporation may limit near-electrode damage during defibrillation; leaves open whether this mechanism alters clinical shock protocols or requires in vivo confirmation.

Structured PICO

P
Population
One-dimensional model of cardiac strand
I
Intervention
Defibrillation shocks via extracellular electrodes inducing electroporation
O
Outcome
Transmembrane potential (Vm)surrogate

Electroporation during defibrillation shocks limits excessive transmembrane potential growth near electrodes, potentially preventing tissue damage without impairing shock delivery to distant myocardium.

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Cite This Study

Wanda Krassowska (1995) studied this question.

synapsesocial.com/papers/6a2080f3df4cd797f4f4228chttps://doi.org/10.1111/j.1540-8159.1995.tb06986.x
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