Pulsed-field ablation for ventricular tachycardia achieved an 88.8% procedural success rate and 100% long-term efficacy with no procedural complications or recurrences across 9 reported cases.
Systematic Review (n=9)
Does pulsed-field ablation improve procedural success and prevent recurrence in patients with ventricular tachycardia?
Pulsed-field ablation shows promising initial safety and efficacy for treating ventricular tachycardia based on early case reports, though larger investigations are urgently needed.
BACKGROUND: Pulsed-field ablation (PFA) is a cutting-edge technique that employs non-thermal energy to cause cell death by inducing irreversible electroporation of cell membranes. This systematic review evaluates the PFA effectiveness as a potential alternative to radiofrequency and cryo-ablation for treating ventricular tachycardia. METHODS: PubMed, Embase, Scopus, and Web of Science were systematically searched using keywords related to ventricular tachycardia and pulsed-field ablation. Eligible Studies evaluating this therapeutic approach for ventricular tachycardia were included in the final analysis. RESULTS: We included six studies (five case reports and one case series) in our systematic review. Eight (88.8%) of procedures were successful with 100% long-term efficacy. No procedural complications or ventricular tachycardia (VT) recurrence were observed in the cases. CONCLUSION: The absence of complications, high effectiveness, and long-term success rate make PFAs a good VT treatment option. However, PFA safety and efficacy studies for VT treatment are scarce. Thus, larger investigations on this topic are urgently needed.
Askarinejad et al. (2024) conducted a systematic review in Ventricular tachycardia (n=9). Pulsed-field ablation was evaluated on Procedural success. Pulsed-field ablation for ventricular tachycardia achieved an 88.8% procedural success rate and 100% long-term efficacy with no procedural complications or recurrences across 9 reported cases.