December 1, 1969Proceedings of the National Academy of Sciences781 citationsOpen Access
Cyclic Nucleotide-Dependent Protein Kinases, Iv. Widespread Occurrence of Adenosine 3′,5′-Monophosphate-Dependent Protein Kinase in Various Tissues and Phyla of the Animal Kingdom
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Abstract
Adenosine 3',5'-monophosphate-dependent protein kinase activity was found in about thirty sources including many mammalian tissues as well as species representative of eight different invertebrate phyla. The data support a unifying theory for the mechanism of action of adenosine 3',5'-monophosphate, namely that its many and diverse effects are mediated through activation of tissue-specific protein kinases.
Cite This Study
Kuo et al. (1969) studied this question.