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June 20, 2026TransfusionOpen Access

A ferritin prediction model to determine individual blood donation frequencies

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Authors

MPMart PothastYPYared PaalvastKHKatja van den Hurk

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Overview

Randomized trial predicts optimal donation frequencies using ferritin and donor metrics, suggesting improved health management.

Key Points

  • This research aims to create a model that predicts ferritin levels to optimize blood donation intervals for donors.
  • Developed a physiology-informed model using baseline ferritin, hemoglobin, and donor metrics.
  • Validated predictions with data from donation records in the Netherlands post-2021.
  • Analyzed the effect of weight and baseline ferritin on predicted levels after multiple donations.
  • The model accurately predicted ferritin levels after five donations, with 71% predictions within measurement uncertainty.
  • Average predictions slightly underestimated actual levels, varying with sex and age.
  • Optimal donation frequency tables were generated based on baseline ferritin and weight influence.

Cite This Study

Pothast et al. (2026) studied this question.

synapsesocial.com/papers/6a363274db0793dc1a5391e7https://doi.org/10.1111/trf.70303
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