Lone AF patients with functional mitral regurgitation had greater mitral valve annular and left atrial areas compared to controls without MR, despite similar LV volumes and ejection fraction.
Case-Control (n=22)
Is functional mitral regurgitation in patients with lone atrial fibrillation associated with mitral annular and left atrial dilation?
In patients with lone atrial fibrillation, functional mitral regurgitation is associated with left atrial and mitral annular dilation rather than left ventricular dysfunction.
BACKGROUND: Whether and how lone atrial fibrillation (AF) is associated with functional mitral regurgitation (MR) remain unclear. METHOD: We studied 12 lone AF patients without left ventricular (LV) dysfunction and/or dilatation, who underwent mitral valve annuloplasty for functional mitral regurgitation (MR). Ten lone AF patients without MR served as controls. RESULTS: Lone AF Patients with MR had a greater mitral valve annular area and left atrial area than those without MR. There were no differences in LV volumes or LV ejection fraction. CONCLUSIONS: Therefore, we concluded that left atrial dilation and corresponding mitral annular dilation may cause MR in lone AF patients without LV dysfunction and/or dilatation.
Kihara et al. (2009) conducted a case-control in Lone atrial fibrillation (n=22). Functional mitral regurgitation vs. No functional mitral regurgitation was evaluated on Mitral valve annular area and left atrial area. Lone AF patients with functional mitral regurgitation had greater mitral valve annular and left atrial areas compared to controls without MR, despite similar LV volumes and ejection fraction.