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The study aims to characterize clinical features and identify risk factors for CMV infection in patients with Good Syndrome.

July 13, 2026BMC ImmunologyOpen Access

Clinical characteristics and risk factors of cytomegalovirus infection in patients with good syndrome

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Retrospective cohort study characterizes CMV infection risk factors in Good Syndrome patients, highlighting implications for clinical management.

The study aims to characterize clinical features and identify risk factors for CMV infection in patients with Good Syndrome.
Retrospective cohort study of GS patients with or without CMV infection.
Data collected from Peking Union Medical College Hospital between January 2015 to December 2024.
Logistic regression and COX model employed to identify factors associated with CMV infection and survival.
15 out of 27 enrolled GS patients developed CMV infection, with notable clinical manifestations including pneumonia and DNAemia.
Lower peripheral blood CD4 + T-cell counts in CMV group (156 vs. 374 cells/µL; P < 0.05).
Logistic regression identified hypoalbuminemia (OR 0.743; P = 0.012) and low serum IgG (OR 0.565; P = 0.041) as significant risk factors for CMV infection.

Chen et al. (2026) studied this question.

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July 13, 2026BMC ImmunologyOpen Access

View Full Paper

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Authors

Retrospective cohort study characterizes CMV infection risk factors in Good Syndrome patients, highlighting implications for clinical management.

The study aims to characterize clinical features and identify risk factors for CMV infection in patients with Good Syndrome.
Retrospective cohort study of GS patients with or without CMV infection.
Data collected from Peking Union Medical College Hospital between January 2015 to December 2024.
Logistic regression and COX model employed to identify factors associated with CMV infection and survival.
15 out of 27 enrolled GS patients developed CMV infection, with notable clinical manifestations including pneumonia and DNAemia.
Lower peripheral blood CD4 + T-cell counts in CMV group (156 vs. 374 cells/µL; P < 0.05).
Logistic regression identified hypoalbuminemia (OR 0.743; P = 0.012) and low serum IgG (OR 0.565; P = 0.041) as significant risk factors for CMV infection.

Chen et al. (2026) studied this question.

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