Current smoking was associated with a significantly higher risk of subarachnoid hemorrhage compared with never smoking without passive exposure (OR 5.0; 95% CI 3.1-8.1).
Case-Control (n=905)
Does active or passive smoking increase the risk of subarachnoid hemorrhage compared to never smoking?
Current smoking is associated with a 5-fold increased risk of subarachnoid hemorrhage, but this risk is virtually eliminated within a few years of smoking cessation.
Odds Ratio: 5 (95% CI 3.1–8.1)
BACKGROUND AND PURPOSE: This study was undertaken to better clarify the risks associated with cigarette smoking and subarachnoid hemorrhage (SAH). METHODS: The study included 432 incident cases of SAH frequency matched to 473 community SAH-free controls to determine dose-dependent associations of active and passive smoking (at home) and smoking cessation with SAH. RESULTS: Compared with never smokers not exposed to passive smoking, the adjusted odds ratio for SAH among current smokers was 5.0 (95% confidence interval CI, 3.1 to 8.1); for past smokers, 1.2 (95% CI, 0.8 to 2.0); and for passive smokers, 0.9 (95% CI, 0.6 to 1.5). Current and lifetime exposures showed a clear dose-dependent effect, and risks appeared more prominent in women and for aneurysmal SAH. Approximately 1 in 3 cases of SAH could be attributed to current smoking, but risks decline quickly after smoking cessation, even among heavy smokers. CONCLUSIONS: A strong positive association was found between cigarette smoking and SAH, especially for aneurysmal SAH and women, which is virtually eliminated within a few years of smoking cessation. Large opportunities exist for preventing SAH through smoking avoidance and cessation programs.
Anderson et al. (Tue,) conducted a case-control in Subarachnoid hemorrhage (n=905). Current smoking vs. Never smokers not exposed to passive smoking was evaluated on Subarachnoid hemorrhage (OR 5.0, 95% CI 3.1 to 8.1). Current smoking was associated with a significantly higher risk of subarachnoid hemorrhage compared with never smoking without passive exposure (OR 5.0; 95% CI 3.1-8.1).